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In 2007, nearly half of patients survived past age 18, up from only 28% who lived that long in 1985, according to the Cystic Fibrosis Foundation.

New drugs now in development also are spreading hope that one day they’ll be able to correct the root cause of cystic fibrosis — flaws in the CF genes inherited from each parent. Four drugs targeting the fundamental cause of CF made by Vertex Pharmaceuticals /quotes/comstock/15*!vrtx/quotes/nls/vrtx (VRTX 33.96, +0.91, +2.75%) , Pharmaxis /quotes/comstock/22x!e:pxs (AU:PXS 2.17, +0.01, +0.46%) , PTC Therapeutics and Inspire Pharmaceuticals /quotes/comstock/15*!isph/quotes/nls/isph (ISPH 5.43, +0.31, +6.05%) are in phase 3 clinical trials, said Laurie Fink, spokeswoman for the Cystic Fibrosis Foundation. In total, there are 30 drugs in the pipeline targeting various aspects of the disease.

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Don